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An engineered PD-1-based and MMP-2/9-oriented fusion protein exerts potent antitumor efficacy agains
Recent studies have shown that PD-1/PD-L1 checkpoint blockade is a dramatic therapy for melanoma through enhancing antit......
BACKGROUND: TMS1/ASC is a bipartite protein comprising two protein-protein interactive domains: pyrin (PYD) and caspase ......
Down-regulation of Bcl-X_L by RNA interference suppresses cell growth and induces apoptosis in human
AIM: To determine the inhibitory effect of the vector- generated small interfering RNAs (siRNAs) on the expression of th......
Alphastatin downregulates vascular endothelial cells sphingosine kinase activity and suppresses tumo
AIM: To investigate whether alphastatin could inhibit human gastric cancer growth and furthermore whether sphingosine ki......
STI571 (Glivec) suppresses the expression of vascular endothelial growth factor in the gastrointesti
AIM:To estimate whether STI571 inhibits the expressionof vascular endothelial growth factor(VEGF)in thegastrointestinal......
Hepatitis B virus(HBV) circulates in blood and replicates in the presence of quasispecies. During HBV replication, HBV D......
Overexpression of C-terminal fragment of glutamate receptor 6 prevents neuronal injury in kainate-in
Our previous study showed that when glutamate receptor(Glu R)6 C terminus-containing peptide conjugated with the human i......
AIM:To investigate urotensin-Ⅱ(UⅡ) and its effects on tumor necrosis factor(TNF)-α and interleukin(IL)-1β in early a......
AIM: To study the effect of hydrogen sulfide(H2S) on severe acute pancreatitis(SAP) in a rat model.METHODS: Sprague-Dawl......
Prof.He Rui’s laboratory at the Department of Immunology,School of Basic Medical Sciences,Fudan University reported the......
Broccoli sprout extract induces detoxification-related gene expression and attenuates acute liver in
AIM: To investigate the effects of broccoli sprout extract(BSEx) on liver gene expression and acute liver injury in the ......
Enterocyte dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin expressio
AIM: To investigate dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin(DC-SIGN) expression ......
It has been shown that in the teleost retina the cone signal transmission seems tobe strongly suppressed in the prolong......
Selective suppression of rod signal transmission by cobalt ions was reported in carp retina. Using 10 μmol/L Co2+ , ro......
The effects of nitric oxide (NO) on electroretinograms and light responses of horizontal cells intra-cellularly recorde......
AIM:To investigate the effect of extracted soybean saponins on the growth of human colon cancer cells.METHODS:WiDr human......
Protein differential expression in the elongating cotton (Gossypium hirsutum L.) fiber under nitroge
Nitrogen (N) is an essential macronutrient and an important factor limiting agricultural productivity. N deficient or ex......
超荧光光纤光源(SFS)具有高稳定性,是光纤传感器(FOSs)中一种理想的光源。SFS光源的相对强度噪声(RIN)是影响FOSs性能的一个重要的......
The effect of Zn 2+ ions codoped on the upconversion emission of Er 3+ ions in Er:LiNbO 3 crystal under different excita......
A series of Fe/HZSM-5 catalysts with different iron loadings were prepared by impregnation method.Characterization was p......
The analysis of seven aliphatic carboxylic acids(formic,acetic,propionic,iso-butyric,n-butyric,iso-valeric and n-valeric......
To enhance the conductivity detection sensitivity of common anions(Na-anions) in electrostatic ion chromatography(EIC) b......
This study investigated the effects of progesterone(P4) on the production and survival of neurons in the hippocampal den......
Nano-sized Ni particles on TiO2-SiO2 were synthesized by the two methods of photo-assisted deposition(PAD) and impregnat......
An obvious antiplasticizing effect has been observed in PVC with small amount of MOCA, 3,3’-dichloro-4,4’-diamino-diph......
A series of manganese spinels LiMn2-yMeyO4 (Me = Li, Al, Mg) were prepared and examined by XRD and electrochemical metho......
Both polymer stabilization and bent-shaped molecule doping strategies are utilized to widen the blue phase range of liqu......
COMPARISON OF CARDIAC ELECTROPHYSIOLOGIC EFFECTS OF EXPERIMENTAL HYPOTHYROIDISM AND CHRONIC ORAL AMI
A comparative study on ventricular electrophysiologic effects of experimental hypothyroidism and chronic oral amiodarone......
High-throughput quantification with label-free methods has received considerable attention in electrospray ionization(ES......
The vortex domains, structural properties and ferroelectric polarization in Y1-xInxMn O3 with 0 B x B 0.6have been exten......
Supercooling of the microencapsulated phase change materials(PCMs) during cooling usually happens.This phenomenon can in......
目的:观察支气管哮喘病儿外周血单个核细胞(PBMC)来源树突状细胞(DC)功能变化。方法:以18例健康儿童为对照,选择16例支气管哮喘发......
Highly selective hydrogenation of halonitroaromatics to aromatic haloamines by ligand modified Ni-ba
Ligand modification of Ni-based catalysts by coordination of dicyandiamide to Ni metal leads to enhanced selectivity for......
Ethylene is Involved but Plays a Limited Role in Tomato Chlorotic Dwarf Viroid-Induced Symptom Devel
To investigate whether ethylene is involved in tomato plants in response to the invasion of viroid, tomato cv. Pearson a......
SUPERCRITICAL CARBON DIOXIDE ASSISTED SYNTHESIS OF AMPHIPHILIC GRAFT COPOLYMERS BASED ON POLY(STYREN
Supercritical carbon dioxide(scCO_2) was used as a reaction medium in synthesizing amphiphilic graft copolymers composed......
RNA silencing is a conserved mechanism found ubiquitously in eukaryotic organisms.It has been used to regulate gene expr......
Single crystals of 4SC(NH2)2–Ni1-xCux Cl2(x = 0.03)(Cu-DTN) containing spin S = 1/2 Cu2+and S = 1 Ni2+cations are synth......
Octahedral Pd@Pt_(1.8)Ni core-shell nanocrystals as efficient catalysts toward oxygen reduction reac
With the support by the National Natural Science Foundation of China,the Ministry of Science and Technology of China,and......
Effect of growth time on morphology and photoelectrochemical performance of TiO_2 nanorod arrays gro
TiO_2 nanorod arrays(NRAs) were synthesized directly on the fluorine tin oxide(FTO) coated glass substrates by a facile ......
Modulation of photovoltaic behavior of dye-sensitized solar cells by electron donors of porphyrin dy
Porphyrin dyes have received great attention due to their excellent photovoltaic performance in dyesensitized solar cell......
EFFECTS OF RAPAMYCIN ON INTRACELLULAR CHOLESTEROL HOMEOSTASIS OF GLOMERULAR MESANGIAL CELL IN THE PR
Objective To investigate the effects of rapamycin on cholesterol homeostasis of glomerular mesangial cells and the under......
Triptolide reduces prostate size and androgen level on testosterone-induced benign prostatic hyperpl
Benign prostatic hyperplasia(BPH) is an age-related disease of unknown etiology, characterized by prostatic enlargement ......
Objective:To evaluate the efficacy of Bawu Decoction(八物汤,BWD,Palmul-tang in Korean)against benign prostatic hyperplas......
Prostate cancer(PCa)is the most common male cancer[1,2].PCa initially depends on androgen receptor(AR)signaling for grow......
NUMERICAL INVESTIGATION OF THE VENTILATED CAVITATING FLOW AROUND AN UNDER-WATER VEHICLE BASED ON A T
Based on the Reynolds-Averaged Navier-Stokes equations and mass transfer model,an approach,where a three-component cavit......
The purpose of this study is to investigate the characteristics of soot particles in C2H4/CO2/O2/N2 combustion at equiva......
A novel function of autism-related protein MeCP2:Interfering with the DGCR8/Drosha complex to suppre
With the support of the National Natural Science Foundation of China and the Ministry of Science and Technology of China......
Systematic variation of the sodium/sulfur promoter content on carbon-supported iron catalysts for th
The Fischer–Tropsch to olefins(FTO) process is a method for the direct conversion of synthesis gas to lower C_2–C_4ole......
Topography,structure,and formation kinetic mechanism of carbon deposited onto nickel in the temperat
The carbon deposition behavior on nickel particles was observed within the temperature range from 400 to 800°C in a pur......
AIM:To explore the influence of hepatic glucose productionon acute insulin resistance induced by a lipid infusion in aw......